Precision Medicine for Pediatric Glioma and NF1-Associated Tumors: The Role of Small Molecule Inhibitors

Pediatric gliomas encompass the most common brain tumor in children and are subdivided into pediatric low-grade gliomas (pLGGs) and pediatric high-grade gliomas (pHGGs). The era of molecular diagnosis has shifted the treatment paradigms and management of these patients. RAS/MAPK pathway alterations...

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Bibliographic Details

Published in:	Current Oncology
Main Authors:	Samuele Renzi, Julie Bennett, Nirav Thacker, Chantel Cacciotti
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Subjects:	glioma MEK inhibitor BRAF inhibitor Pan-RAF inhibitor FGFR inhibitor TRK inhibitor
Online Access:	https://www.mdpi.com/1718-7729/32/5/280