Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases

BACKGROUND We previously demonstrated the safety of stereotactic body radiotherapy followed by pembrolizumab (SBRT+P) in patients with advanced solid tumors. This phase I clinical trial was expanded to study the safety of partial tumor irradiation (partial-Rx). We assessed irradiated local failure (...

Full description

Bibliographic Details

Published in:	The Journal of Clinical Investigation
Main Authors:	Mark C. Korpics, Benjamin E. Onderdonk, Rebekah E. Dadey, Jared H. Hara, Lilit Karapetyan, Yuanyuan Zha, Theodore G. Karrison, Adam C. Olson, Gini F. Fleming, Ralph R. Weichselbaum, Riyue Bao, Steven J. Chmura, Jason J. Luke
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2023-05-01
Subjects:	Clinical trials Oncology
Online Access:	https://doi.org/10.1172/JCI162260