Transformation of t(14;18)-negative follicular lymphoma to plasmablastic lymphoma: a case report with analysis of genetic evolution

Abstract Background Follicular lymphoma (FL) is characterized by t(14;18)(q32;q21) involving the IGH and BCL2 genes. However, 10–15% of FLs lack the BCL2 rearrangement. These BCL2-rearrangement−negative FLs are clinically, pathologically, and genetically heterogeneous. The biological behavior and hi...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Diagnostic Pathology
المؤلفون الرئيسيون:	Sojung Lim, Jiwon Koh, Jeong Mo Bae, Hongseok Yun, Cheol Lee, Jin Ho Paik, Tae Min Kim, Yoon Kyung Jeon
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2024-06-01
الموضوعات:	BCL2-rearrangement−negative follicular lymphoma Plasmablastic lymphoma Histological transformation Clonal evolution Targeted gene sequencing
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13000-024-01512-2