Mechanical forces rewire metabolism in the tumor niche

Tumor niche extracellular matrix stiffening and tumor cell metabolic reprogramming are two fundamental mediators of tumor progression. We recently elucidated a mechanistic interconnection between mechanotransduction and tumor metabolic rewiring in cancer. We demonstrated a stiffness-dependent amino...

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Bibliographic Details
Published in:Molecular & Cellular Oncology
Main Authors: Thomas Bertero, Cedric Gaggioli
Format: Article
Language:English
Published: Taylor & Francis Group 2019-05-01
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2019.1592945