2-Amino-1,3-benzothiazole: Endo <i>N</i>-Alkylation with α-Iodo Methyl Ketones Followed by Cyclization

Reactions of 2-amino-1,3-benzothiazole with aliphatic, aromatic and heteroaromatic α-iodoketones in the absence of bases or catalysts have been studied. The reaction proceeds by N-alkylation of the endocyclic nitrogen atom followed by intramolecular dehydrative cyclization. The regioselectivity is e...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Ivan A. Dorofeev, Larisa V. Zhilitskaya, Nina O. Yarosh, Bagrat A. Shainyan
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	2-amino-1,3-benzothiazole iodoacetone 1,3-diiodoacetone aromatic heteroaromatic α-iodo methyl ketones N-alkylation
Online Access:	https://www.mdpi.com/1420-3049/28/5/2093