Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon

ABSTRACT Dengue virus (DENV) is the most widespread arbovirus, causing symptoms ranging from dengue fever to severe dengue, including hemorrhagic fever and shock syndrome. Four serotypes of DENV (DENV-1 to -4) can infect humans; however, no anti-DENV drug is available. To facilitate the study of ant...

Full description

Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Mingyue Hu, Wan-Fei Li, Tiantian Wu, Yang Yang, Guoquan Chen, Tongling Chen, Yongchen Liu, Yaqing Mei, De Wu, Youchuan Wei, Tingrong Luo, Hong-Jie Zhang, Yi-Ping Li
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-08-01
Subjects:	DENV adaptive mutation antiviral compound arylnaphthalene lignans infectious clone replicon
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00423-23