Exploiting nucleotide composition to engineer promoters.

The choice of promoter is a critical step in optimizing the efficiency and stability of recombinant protein production in mammalian cell lines. Artificial promoters that provide stable expression across cell lines and can be designed to the desired strength constitute an alternative to the use of vi...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Manfred G Grabherr, Jens Pontiller, Evan Mauceli, Wolfgang Ernst, Martina Baumann, Tara Biagi, Ross Swofford, Pamela Russell, Michael C Zody, Federica Di Palma, Kerstin Lindblad-Toh, Reingard M Grabherr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3097237?pdf=render

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http://europepmc.org/articles/PMC3097237?pdf=render

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