Targeting the inhibitors of apoptosis proteins (IAPs) to combat drug resistance in cancers

Inhibitors of Apoptosis Proteins (IAPs) are a family of anti-apoptotic proteins that play a pivotal role in apoptosis in general but also as oncoproteins in cancer progression and, more importantly, drug resistance. IAPs enable cancer cells to evade programmed cell death and adapt to therapeutic str...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Qingmei Ye, Xiao-Zhao Zhuang, Juan Li, Xin Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	drug resistance cancer inhibitors of apoptosis proteins inhibitors overcome
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1562167/full