Multidrug Resistance Reversal Effects of Aminated Thioxanthones and Interaction with Cytochrome P450 3A4

Purpose. Aminated thioxanthones have recently been described as dual-acting agents: growth inhibitors of leukemia cell lines and P-glycoprotein (P-gp) inhibitors. To evaluate the selectivity profile of thioxanthones as inhibitors of multidrug resistance (MDR), their interaction with other ABC transp...

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Bibliographic Details

Published in:	Journal of Pharmacy & Pharmaceutical Sciences
Main Authors:	Andreia Palmeira, Maria Emília Sousa, Miguel X Fernandes, Madalena M. Pinto, M. Helena Vasconcelos
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2011-12-01
Online Access:	https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/11714