Macrophage Polarization in Chronic Lymphocytic Leukemia: Nurse-Like Cells Are the Caretakers of Leukemic Cells

Macrophages are terminally differentiated innate immune cells. Through their activation, they can be polarized towards the pro-inflammatory M1 type or the wound healing-associated, anti-inflammatory M2 type macrophages. In the tumor microenvironment (TME), M2 is the dominant phenotype and these cell...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Oana Mesaros, Laura Jimbu, Alexandra Neaga, Cristian Popescu, Iulia Berceanu, Ciprian Tomuleasa, Bogdan Fetica, Mihnea Zdrenghea
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Subjects:	macrophages CLL nurse-like cells
Online Access:	https://www.mdpi.com/2227-9059/8/11/516