Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels

Hypoxia benefits the proliferation and maintenance of animal spermatogonial cells; however, the underlying mechanism remains incompletely understood. This study aims to investigate the role and mechanism of the hypoxia–glycolysis–histone lactylation axis in the proliferation of buffalo spermatogonia...

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Bibliographic Details

Published in:	Cells
Main Authors:	Mengqi Li, Yanyu Ma, Shenzhi Wang, Haiying Zheng, Chunyan Yang, Anqin Duan, Benliang Zhou, Jianghua Shang, Xingwei Liang, Xiaogan Yang
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Subjects:	spermatogonial cells hypoxia proliferation histone lactylation buffalo
Online Access:	https://www.mdpi.com/2073-4409/14/11/832