Combinatorial Genomic Biomarkers Associated with High Response in IgE-Dependent Degranulation in Human Mast Cells

Mast cells are the major effector cells that mediate IgE-dependent allergic reactions. We sought to use integrated network analysis to identify genomic biomarkers associated with high response in IgE-mediated activation of primary human mast cells. Primary human mast cell cultures derived from 262 n...

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Bibliographic Details

Published in:	Cells
Main Authors:	Issan Yee San Tam, Tak Hong Lee, Hang Yung Alaster Lau, See-Ying Tam
Format:	Article
Language:	English
Published:	MDPI AG 2024-07-01
Subjects:	inflammation allergy immunoglobulin E mast cell degranulation integrated network analysis genomic biomarkers
Online Access:	https://www.mdpi.com/2073-4409/13/15/1237