Gelatin-Based Electrospun Nanofibers Cross-Linked Using Horseradish Peroxidase for Plasmid DNA Delivery

The delivery of nucleic acids is indispensable for tissue engineering and gene therapy. However, the current approaches involving DNA/RNA delivery by systemic and local injections face issues such as clearance, off-target distribution, and tissue damage. In this study, we report plasmid DNA (pDNA) d...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Kotoko Furuno, Keiichiro Suzuki, Shinji Sakai
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/11/1638