DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes

Abstract Background Individuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age estimation through DNA methylation (DNAm), i.e. the epigenetic clocks, is emerging as a possible tool to improve risk stratification for multiple...

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Bibliographic Details

Published in:	Cardiovascular Diabetology
Main Authors:	Jacopo Sabbatinelli, Angelica Giuliani, Katarzyna Malgorzata Kwiatkowska, Giulia Matacchione, Alessia Belloni, Deborah Ramini, Francesco Prattichizzo, Valeria Pellegrini, Francesco Piacenza, Elena Tortato, Anna Rita Bonfigli, Davide Gentilini, Antonio Domenico Procopio, Paolo Garagnani, Fabiola Olivieri, Giuseppe Bronte
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Subjects:	Type 2 diabetes Epigenetic clocks DNA methylation PhenoAge DunedinPoAm
Online Access:	https://doi.org/10.1186/s12933-024-02351-7