Influence of Ionization and the Addition of Cyclodextrins and Hydrophilic Excipients on the Solubility of Benzthiazide, Isoxicam, and Piroxicam

<b>Background</b>: The bioavailability of a drug depends, among other parameters, on solubility. One of the strategies used to enhance the solubility of sparingly soluble drugs is the use of excipients. Excipients can interact with the drug by increasing its solubility and/or stabilizing...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Diego Lucero-Borja, Rebeca Ruiz, Elisabet Fuguet, Clara Ràfols
Format: Article
Language:English
Published: MDPI AG 2025-04-01
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Online Access:https://www.mdpi.com/1999-4923/17/5/571