Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy.

Here we report label-free optical imaging of single particles of the influenza virus attached on a glass surface with a simple objective-type total internal reflection dark-field microscopy (TIRDFM). The capability of TIRDFM for the imaging of single viral particles was confirmed from fine correlati...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Sawako Enoki, Ryota Iino, Nobuhiro Morone, Kunihiro Kaihatsu, Shouichi Sakakihara, Nobuo Kato, Hiroyuki Noji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:http://europepmc.org/articles/PMC3499535?pdf=render