Peripheral Immune Profiles in Individuals at Genetic Risk of Amyotrophic Lateral Sclerosis and Alzheimer’s Disease

The immune system plays a crucial role in the pathogenesis of neurodegenerative diseases. Here, we explored whether blood immune cell profiles are already altered in healthy individuals with a genetic predisposition to amyotrophic lateral sclerosis (ALS) or Alzheimer’s disease (AD). Using multicolor...

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Bibliographic Details
Published in:Cells
Main Authors: Laura Deecke, Olena Ohlei, David Goldeck, Jan Homann, Sarah Toepfer, Ilja Demuth, Lars Bertram, Graham Pawelec, Christina M. Lill
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Subjects:
immune system
immune cell
neurodegeneration
polygenic risk score
disease prediction
Online Access:https://www.mdpi.com/2073-4409/14/4/250

Internet

https://www.mdpi.com/2073-4409/14/4/250

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