Leptin is required for hypothalamic regulation of miRNAs targeting POMC 3’UTR

The central nervous system monitors modifications in metabolic parameters or hormone levels and elicits adaptive responses such as food intake regulation. Particularly, within the hypothalamus, leptin modulates the activity of pro-opiomelanocortin (POMC) neurons which are critical regulators of ener...

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Bibliographic Details
Published in:Frontiers in Cellular Neuroscience
Main Authors: Adel eDerghal, Mehdi eDjelloul, Coraline eAirault, Clémént ePierre, Michel eDallaporta, Jean-Denis eTroadec, Vanessa eTillement, Catherine eTardivel, Bruno eBariohay, Jérôme eTrouslard, Lourdes eMounien
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Subjects:
Hypothalamus
Leptin
microRNA
food intake
melanocortin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00172/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00172/full

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