RNAseq of INOCA patients identifies innate, invariant, and acquired immune changes: potential autoimmune microvascular dysfunction

BackgroundIschemia with non-obstructive coronary arteries (INOCA) is a major clinical entity that involves potentially 20%–30% of patients with chest pain. INOCA is typically attributed either to coronary microvascular disease and/or vasospasm, but is likely distinct from classical coronary artery d...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Kevin Jaatinen, Palak Shah, Ramesh Mazhari, Zane Hayden, Richard Wargowsky, Tisha Jepson, Ian Toma, John Perkins, Timothy A. McCaffrey
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	INOCA RNAseq MAIT (mucosal-associated invariant T) cell coronary artery disease T cell neutrophil
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2024.1385457/full