Assessing the effect of moderately increasing medium viscosity on the intrinsic dissolution rate and diffusion coefficient of ibuprofen particles

This study investigated the effects of moderately increasing medium viscosity through two viscosity enhancing agents (VEA) (HPMC and sucrose) on the intrinsic dissolution of a BCS class II drug (ibuprofen). The differences in intrinsic dissolution were characterized through the estimation of a diffu...

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Bibliographic Details
Published in:British Journal of Pharmacy
Main Authors: Marina Navas Bachiller, Tim Persoons, Anne-Marie Healy, Deirdre Maria D'Arcy
Format: Article
Language:English
Published: University of Huddersfield Press 2022-11-01
Subjects:
dissolution
viscosity
ibuprofen
diffusion
Online Access:https://www.bjpharm.org.uk/article/id/1130/

Internet

https://www.bjpharm.org.uk/article/id/1130/

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