Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci

Abstract Background Single-variant associations with age-related macular degeneration (AMD), one of the most prevalent causes of irreversible vision loss worldwide, have been studied extensively. However, because of a lack of refinement of these associations, there remains considerable ambiguity reg...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Human Genomics
المؤلفون الرئيسيون: Chris M. Pappas, Moussa A. Zouache, Stacie Matthews, Caitlin D. Faust, Jill L. Hageman, Brandi L. Williams, Burt T. Richards, Gregory S. Hageman
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2021-09-01
الموضوعات:
Age-related macular degeneration
CFH-CFHR5
ARMS2/HTRA1
Haplotype
Diplotype
Genetic association study
الوصول للمادة أونلاين:https://doi.org/10.1186/s40246-021-00359-8

الانترنت

https://doi.org/10.1186/s40246-021-00359-8

مواد مشابهة