Evolution of protective SARS-CoV-2-specific B and T cell responses upon vaccination and Omicron breakthrough infection

Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron breakthrough infection (BTI) induced better protection than triple vaccination. To address the underlying immunological mechanisms, we studied antibody and T cell response dynamics during vaccination and after BTI. Each va...

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Bibliographic Details
Published in:iScience
Main Authors: Mohamed I.M. Ahmed, Sebastian Einhauser, Clemens Peiter, Antonia Senninger, Olga Baranov, Tabea M. Eser, Manuel Huth, Laura Olbrich, Noemi Castelletti, Raquel Rubio-Acero, George Carnell, Jonathan Heeney, Inge Kroidl, Kathrin Held, Andreas Wieser, Christian Janke, Michael Hoelscher, Jan Hasenauer, Ralf Wagner, Christof Geldmacher
Format: Article
Language:English
Published: Elsevier 2024-06-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224013634