BDNF/TrkB axis activation promotes epithelial–mesenchymal transition in idiopathic pulmonary fibrosis

Abstract Background Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and disease. Here we investigated the expressi...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Emanuela Cherubini, Salvatore Mariotta, Davide Scozzi, Rita Mancini, Giorgia Osman, Michela D’Ascanio, Pierdonato Bruno, Giuseppe Cardillo, Alberto Ricci
Format:	Article
Language:	English
Published:	BMC 2017-09-01
Subjects:	BDNF TrkB EMT Idiopathic pulmonary fibrosis Lung
Online Access:	http://link.springer.com/article/10.1186/s12967-017-1298-1