Revealing oxidative stress-related genes in osteoporosis and advanced structural biological study for novel natural material discovery regarding MAPKAPK2

ObjectivesThis study aimed to find novel oxidative stress (OS)-related biomarkers of osteoporosis (OP), together with targeting the macromolecule Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2) protein to further discover potential novel materials based on an advanced structur...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Yingjing Zhao, Weihang Li, Kuo Zhang, Meng Xu, Yujia Zou, Xiaotong Qiu, Tianxing Lu, Bo Gao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Subjects:	high-throughput virtual screening osteoporosis WGCNA MAPKAPK2 targeted therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.1052721/full