Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex

HNRNPU is an RNA splicing protein associated with brain disorders such as early onset seizures. Here they show that HNRNPU functions to maintain neural progenitors and their progeny by regulating splicing of key neuronal genes.

Bibliographic Details
Published in:Nature Communications
Main Authors: Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Online Access:https://doi.org/10.1038/s41467-022-31752-z

Internet

https://doi.org/10.1038/s41467-022-31752-z

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