The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells

Patients diagnosed with isocitrate dehydrogenase mutant (IDH^mut) gliomas suffer frequently from seizures. Although the clinical course is less aggressive than that of its IDH wildtype counterpart, recent discoveries have shown that epileptic activity can promote tumor prolifer...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Philip Dao Trong, Gerhard Jungwirth, Andreas Unterberg, Christel Herold-Mende, Rolf Warta
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Subjects:	isocitrate dehydrogenase mutation antiepileptic drugs repurposing drug screen glioma stem cells oxcarbazepine perampanel
Online Access:	https://www.mdpi.com/2073-4409/12/8/1200