Downregulated miRNA-491-3p accelerates colorectal cancer growth by increasing uMtCK expression

Colorectal carcinoma (CRC) is the second most frequent cancer worldwide. MiR-491-3p, a tumor-suppressive microRNA (miRNA, miR), has been revealed to be abnormally expressed in CRC tissues. Meanwhile, up-regulated ubiquitous mitochondrial creatine kinase (uMtCK) contributes to CRC cell proliferation....

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Bibliographic Details
Published in:PeerJ
Main Authors: Xingkui Tang, Yukun Lin, Jialin He, Xijun Luo, Junjie Liang, Xianjun Zhu
Format: Article
Language:English
Published: PeerJ Inc. 2022-11-01
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Online Access:https://peerj.com/articles/14285.pdf