Reproductive aging in biological females: mechanisms and immediate consequences

Reproductive aging is a dynamic, systemic process that encompasses more than the decline in ovarian function. It involves coordinated changes across neuroendocrine, immune, metabolic, and mitochondrial systems. Central to this transition is the depletion of ovarian follicles, leading to reduced estr...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Author:	Yasin Ali Muhammad
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	aging endocrine system menopause (estrogen withdrawal) ovarian follicle cells hypothalamas
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1658592/full