Genomic variation as a marker of response to neoadjuvant therapy in locally advanced rectal cancer

There is variation in the responsiveness of locally advanced rectal cancer to neoadjuvant chemoradiation, from complete response to total resistance. This study compared genetic variation in rectal cancer patients who had a complete response to chemoradiation versus poor response, using tumor tissue...

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Bibliographic Details

Published in:	Molecular & Cellular Oncology
Main Authors:	Jason K. Douglas, Rose E. Callahan, Zachary A. Hothem, Craig S. Cousineau, Samer Kawak, Bryan J. Thibodeau, Shelli Bergeron, Wei Li, Claire E. Peeples, Harry J. Wasvary
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-05-01
Subjects:	rectal cancer biomarkers chemoradiation neoadjuvant treatment therapeutic response genetic variation
Online Access:	http://dx.doi.org/10.1080/23723556.2020.1716618