Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response.

Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-β, influences interferon (IFN) production by primary bronchial epithelial cells (PBECs) following...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Nicole Bedke, David Sammut, Ben Green, Valia Kehagia, Patrick Dennison, Gisli Jenkins, Amanda Tatler, Peter H Howarth, Stephen T Holgate, Donna E Davies
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0044580&type=printable