Metabolic Reprogramming toward Aerobic Glycolysis and the Gut Microbiota Involved in the Brain Amyloid Pathology

Alzheimer’s disease (AD) is characterized by the formation of senile plaques consisting of fibrillated amyloid-β (Aβ), dystrophic neurites, and the neurofibrillary tangles of tau. The oligomers/fibrillar Aβ damages the neurons or initiates an intracellular signaling cascade for neuronal cell death l...

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發表在:	Biology
Main Authors:	Toshiyuki Murai, Satoru Matsuda
格式:	Article
語言:	英语
出版:	MDPI AG 2023-08-01
主題:	glucose metabolism aerobic glycolysis Warburg effect Alzheimer’s disease amyloid-β ketogenic diet
在線閱讀:	https://www.mdpi.com/2079-7737/12/8/1081