Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

Proton-pump inhibitors (PPIs), frequently prescribed to lower gastric acid secretion, often exert an effect on the absorption of co-medicated drug products. A previous study showed decreased plasma levels of the lipophilic drug ritonavir after co-administration with the PPI Nexium (40 mg esomeprazol...

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發表在:	Pharmaceutics
Main Authors:	Tom de Waal, Jari Rubbens, Michael Grimm, Vincent Vandecaveye, Jan Tack, Werner Weitschies, Joachim Brouwers, Patrick Augustijns
格式:	Article
語言:	英语
出版:	MDPI AG 2020-07-01
主題:	MRI PPI effect ritonavir gastric fluid volume intestinal fluid volume drug absorption
在線閱讀:	https://www.mdpi.com/1999-4923/12/7/670