Heterocyclization vs Coupling Reactions: A DNA-Encoded Libraries Case

Aim. DNA-encoded libraries technologies (DELT) are gradually becoming an important part of standard drug discovery toolbox. DELT is looking to find its place between classic low-molecular-weight drug candidates on the one hand, and high-molecular-weight antibodies and peptides on the other hand. On...

全面介紹

書目詳細資料

發表在:	Журнал органічної та фармацевтичної хімії
Main Authors:	Oleksandr V. Oksiuta, Alexander E. Pashenko, Radomyr V. Smalii, Dmitry M. Volochnyuk, Serhii V. Ryabukhin
格式:	Article
語言:	英语
出版:	National University of Pharmacy (Kharkiv) 2023-04-01
主題:	dna-encoded libraries technology orthogonal functional groups coupling reactions polyfunctional building blocks heterocyclizations chemoinformatics scaffold diversity
在線閱讀:	http://ophcj.nuph.edu.ua/article/view/275133