Kinetic Analysis Misinterpretations Due to the Occurrence of Enzyme Inhibition by Reaction Product: Comparison between Initial Velocities and Reaction Time Course Methodologies

The Michaelis–Menten equation (MME) has been extensively used in biochemical reactions, but it is not appropriate when the reaction product inhibits the enzyme. Under these circumstances, each determined initial velocity, v<sub>0</sub>, is one experimental point that actually belongs to...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Applied Sciences
المؤلفون الرئيسيون: Joana M. C. Fernandes, Albino A. Dias, Rui M. F. Bezerra
التنسيق: مقال
اللغة:الإنجليزية
منشور في: MDPI AG 2021-12-01
الموضوعات:
enzyme inhibition
integrated Michaelis–Menten equations
reaction product inhibition
two mutually exclusive inhibitors
الوصول للمادة أونلاين:https://www.mdpi.com/2076-3417/12/1/102

الانترنت

https://www.mdpi.com/2076-3417/12/1/102

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