A Chimeric Cationic Peptide Composed of Human β-Defensin 3 and Human β-Defensin 4 Exhibits Improved Antibacterial Activity and Salt Resistance

Human beta-defensins (hBDs) play an important role in the host defense against various microbes, showing different levels of antibacterial activity and salt resistance in vitro. It is of interest to investigate whether can chimeric hBD analogs enhanced antibacterial activity and salt resistance. In...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Wenjing Yu, Nianzhi Ning, Ying Xue, Yanyu Huang, Feng Guo, Tao Li, Boning Yang, Deyan Luo, Yakun Sun, Zhan Li, Jianxin Wang, Zhili He, Shiwei Cheng, Xingxiao Zhang, Hui Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Subjects:	human beta-defensins antibacterial activity salt resistance chimeric human defensin multidrug resistant
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.663151/full