Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. As with the majority of neurodegenerative diseases, the pathological hallmarks of ALS involve proteinopathies which lead to the formation o...

书目详细资料
发表在:	Frontiers in Neuroscience
Main Authors:	Bridget C. Benson, Pamela J. Shaw, Mimoun Azzouz, J. Robin Highley, Guillaume M. Hautbergue
格式:	文件
语言:	英语
出版:	Frontiers Media S.A. 2021-12-01
主题:	proteinopathies RNA metabolism alteration mitochondrial dysfunction impaired proteostasis amyotrophic lateral sclerosis
在线阅读:	https://www.frontiersin.org/articles/10.3389/fnins.2021.783624/full

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