Proteinopathies as Hallmarks of Impaired Gene Expression, Proteostasis and Mitochondrial Function in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. As with the majority of neurodegenerative diseases, the pathological hallmarks of ALS involve proteinopathies which lead to the formation o...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Frontiers in Neuroscience
المؤلفون الرئيسيون:	Bridget C. Benson, Pamela J. Shaw, Mimoun Azzouz, J. Robin Highley, Guillaume M. Hautbergue
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2021-12-01
الموضوعات:	proteinopathies RNA metabolism alteration mitochondrial dysfunction impaired proteostasis amyotrophic lateral sclerosis
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fnins.2021.783624/full

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