A rapid and sensitive extraction-free HiFi-LAMP assay for detecting Mycobacterium leprae

Background: Timely and accurate detection of Mycobacterium leprae (M. leprae) is crucial for efficient treatment and early intervention of leprosy, which requires a simple and rapid extraction-free assay. Methods: A HiFi-loop-mediated isothermal amplification (LAMP) assay was developed for detection...

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Bibliographic Details

Published in:	International Journal of Infectious Diseases
Main Authors:	Zhengfang Wang, Xi Yang, Zhi-Ze Wang, Xiu-Feng Yu, Zhe Li, Shangwen Song, Yongjuan Zhao, Yi-Qun Kuang, Yu-Ye Li, Chiyu Zhang
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	M. leprae HiFi-LAMP Extraction-free Saliva Point-of-care testing (POCT) Nested PCR
Online Access:	http://www.sciencedirect.com/science/article/pii/S120197122500058X