β-sitosterol alleviates atherosclerosis by regulating catalase

The aim of this study is to investigate the main active components of Gegen (Puerariae Lobatae Radix) on atherosclerosis and its mechanism of action. Bioinformatics analysis showed that β-sitosterol was the most likely active ingredient to mediate the anti-atherosclerotic effects. In vivo experiment...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Shuntao Jiang, Kui Gao, Furong Zhang, Yanli Wang, Xiaojing He, Jun Yang
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	Puerariae lobatae radix β-sitosterol Atherosclerosis Lipid deposition VSMCs phenotypic transformation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024116702