Example for process validation in biobanking: Fit for purpose testing of a cryopreservation method without isopentane

Background: The freezing process of tissue samples is crucial for the preservation of morphological and molecular features. Several biobanking guidelines describe freezing techniques for optimal outcomes. As the Vetbiobank standard freezing protocol does not comply with those recommendations in deta...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Monika Wieser, Stefanie Burger, Reinhard Ertl, Stefan Kummer, Melanie Stargardt, Ingrid Walter
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Subjects:	biobanking process validation snap-freezing tissue morphology RNA integrity
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.876670/full