Type 2 diabetes mellitus facilitates status epilepticus in adult rats: Seizure severity, neurodegeneration, and oxidative stress

Abstract Objective The goal of this research was to evaluate the effect of DM type 2 (DM2) on SE severity, neurodegeneration, and brain oxidative stress (OS) secondary to seizures. Methods DM2 was induced in postnatal day (P) 3 male rat pups by injecting streptozocin (STZ) 100 mg/kg; control rats we...

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Bibliographic Details
Published in:Epilepsia Open
Main Authors: Karen Paola Ramos‐Riera, Luis Beltrán‐Parrazal, Consuelo Morgado‐Valle, Francisca Pérez‐Severiano, Pablo Eliasib Martínez‐Gopar, María Leonor López‐Meraz
Format: Article
Language:English
Published: Wiley 2024-04-01
Subjects:
hyperglycemia
oxidative stress
seizures
status epilepticus
streptozocin
Online Access:https://doi.org/10.1002/epi4.12905

Internet

https://doi.org/10.1002/epi4.12905

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