Thermo-Responsive Hydrogel Based on Lung Decellularized Extracellular Matrix for 3D Culture Model to Enhance Cancer Stem Cell Characteristics

Cancer stem cells (CSCs) are most likely the main cause of lung cancer formation, metastasis, drug resistance, and genetic heterogeneity. Three-dimensional (3D) ex vivo cell culture models can facilitate stemness improvement and CSC enrichment. Considering the critical role of extracellular matrix (...

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Bibliographic Details
Published in:Molecules
Main Authors: Lei Chen, Fanglu Li, Ruobing Li, Ke Zheng, Xinyi Zhang, Huijing Ma, Kaiming Li, Lei Nie
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/18/4385