Developmental enhancement of adenylate kinase-AMPK metabolic signaling axis supports stem cell cardiac differentiation.

<h4>Background</h4>Energetic and metabolic circuits that orchestrate cell differentiation are largely unknown. Adenylate kinase (AK) and associated AMP-activated protein kinase (AMPK) constitute a major metabolic signaling axis, yet the role of this system in guiding differentiation and...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Petras P Dzeja, Susan Chung, Randolph S Faustino, Atta Behfar, Andre Terzic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019300&type=printable