Identification of sleep fragmentation-induced gut microbiota alteration and prediction of functional impact in Sprague Dawley rats harboring microbiome derived from multiple human donors

Objectives: Poor quality sleep, including sleep fragmentation (SF), can result in severe health consequences. Gut microbiota symbiotically coexist with the host, making essential contributions to overall well-being. In this study, the effects of both acute (6-day) and chronic (6-week) SF in a humani...

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Bibliographic Details

Published in:	Sleep Science
Main Authors:	Judy Triplett, Amber Braddock, Erin Roberts, David Ellis, Victor Chan
Format:	Article
Language:	English
Published:	Thieme Revinter Publicações Ltda.
Subjects:	sleep fragmentation sleep disturbances gut microbiota humanized rat model metagenomics 16s rrna
Online Access:	https://cdn.publisher.gn1.link/sleepscience.org.br/pdf/v15nspea02.pdf