Profile of Basal Cell Carcinoma Mutations and Copy Number Alterations - Focus on Gene-Associated Noncoding Variants

Basal cell carcinoma (BCC) of the skin is the most common cancer in humans, characterized by the highest mutation rate among cancers, and is mostly driven by mutations in genes involved in the hedgehog pathway. To date, almost all BCC genetic studies have focused exclusively on protein-coding sequen...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Paulina Maria Nawrocka, Paulina Galka-Marciniak, Martyna Olga Urbanek-Trzeciak, Ilamathi M-Thirusenthilarasan, Natalia Szostak, Anna Philips, Laura Susok, Michael Sand, Piotr Kozlowski
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-11-01
Subjects:	basal cell carcinoma (BCC) cancer somatic mutations noncoding mutations immune checkpoint copy number alterations cancer drivers
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.752579/full