ARHGAP18-ezrin functions as an autoregulatory module for RhoA in the assembly of distinct actin-based structures

The location of different actin-based structures is largely regulated by Rho GTPases through specific effectors. We use the apical aspect of epithelial cells as a model system to investigate how RhoA is locally regulated to contribute to two distinct adjacent actin-based structures. Assembly of the...

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Bibliographic Details
Published in:eLife
Main Authors: Andrew T Lombardo, Cameron AR Mitchell, Riasat Zaman, David J McDermitt, Anthony Bretscher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Subjects:
actin
microvilli
polarity
Rho GAP
ezrin
Online Access:https://elifesciences.org/articles/83526

Internet

https://elifesciences.org/articles/83526

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