Unraveling cooperative and competitive interactions within protein triplets in the human interactome

Abstract Knowledge of protein–protein interactions (PPIs) is essential for understanding cellular function, yet most network analyses focus on binary interactions. Higher-order motifs such as protein triplets can reveal cooperative or competitive relationships but are difficult to distinguish system...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Aimilia-Christina Vagiona, Pablo Mier, Miguel A. Andrade-Navarro
Format: Article
Language:English
Published: Nature Portfolio 2025-09-01
Online Access:https://doi.org/10.1038/s41598-025-19264-4