Host–Guest Interaction Study of Olmesartan Medoxomil with β-Cyclodextrin Derivatives

Olmesartan medoxomil (OLM) is a selective angiotensin II receptor antagonist used in the treatment of hypertension. Its therapeutic potential is limited by its poor water solubility, leading to poor bioavailability. Encapsulation of the drug substance by two methylated cyclodextrins, namely randomly...

Full description

Bibliographic Details

Published in:	Molecules
Main Authors:	Minodora Andor, Claudia Temereancă, Laura Sbârcea, Adriana Ledeți, Dana Emilia Man, Cristian Mornoș, Amalia Ridichie, Denisa Cîrcioban, Gabriela Vlase, Paul Barvinschi, Angela Caunii, Renata-Maria Văruţ, Cristina Maria Trandafirescu, Valentina Buda, Ionuț Ledeți, Matilda Rădulescu
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	olmesartan medoxomil cyclodextrins inclusion complex molecular encapsulation solubility enhancement spectroscopic methods
Online Access:	https://www.mdpi.com/1420-3049/29/10/2209