Acteoside protects podocyte against apoptosis through regulating AKT/GSK-3β signaling pathway in db/db mice

Abstract Background Podocyte apoptosis is one of the important pathological mechanisms of diabetic kidney disease (DKD). Acteoside (Act), a major active component of Rehmannia glutinosa leaves total glycoside, has a strong renoprotective action. Our study aims to demonstrate Act’s renoprotective act...

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Bibliographic Details
Published in:BMC Endocrine Disorders
Main Authors: Xiaoya Li, Zhilong Liu, Zhixiu He, Xiaocheng Wang, Rongshan Li, Junwei Wang, Guiqiao Ma, Peipei Zhang, Chanjuan Ma
Format: Article
Language:English
Published: BMC 2023-10-01
Subjects:
Diabetic Kidney Disease (DKD)
Acteoside
Podocyte
Apoptosis
AKT/GSK-3β signaling pathway
Online Access:https://doi.org/10.1186/s12902-023-01483-3

Internet

https://doi.org/10.1186/s12902-023-01483-3

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