Sensitivity of EGFR/HER-2 Positive Cells Isolated from Ascitic Fluid of Advanced Ovarian Cancer Patients to EGFR/HER-2 Inhibitors

Background: advanced ovarian cancer often presents with ascites. These ascites contain small clusters of cancer cells, which may contribute greatly to the metastatic potential of ovarian cancer in the peritoneal cavity. Therefore, understanding the unique protein expressions of this cell population...

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Bibliographic Details

Published in:	Applied Sciences
Main Authors:	Kenny Chitcholtan, Dianne Harker, Bryony Simcock, Peter Sykes
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Subjects:	ovarian cancer cell clusters EGFR HER-2 gefitinib canertinib
Online Access:	https://www.mdpi.com/2076-3417/10/7/2343