SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation
Abstract Some exciting biological questions require quantifying thousands of proteins in single cells. To achieve this goal, we develop Single Cell ProtEomics by Mass Spectrometry (SCoPE-MS) and validate its ability to identify distinct human cancer cell types based on their proteomes. We use SCoPE-...
| Published in: | Genome Biology |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-10-01
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| Online Access: | http://link.springer.com/article/10.1186/s13059-018-1547-5 |